Our Works
The organization of our team around the original theme “Cancer and Cognition” led to a a number of scientific advances
Cog-Age : Impact of adjuvant chemotherapy on cognitive functions and quality of life of patients over the age of 65: application to breast cancer
Clinical/Neuropsychological/Biostatistics
CanMem : Impact of cancer on functional memory: improving the understanding of impairment using neuropsychological approaches and neuroimaging (complementary project to Cog-Age)
Neuropsychological
Cog-Angio : Impact of anti-angiogenic treatments on quality of life and cognitive functions of metastatic renal cell carcinoma adult patients.
Clinical/Neuropsychological/Biostatistics
Cog-Obs : Impact of cognitive functions on observance in patients with oral cancer therapies.
Clinical/Neuropsychological/Biostatistics
Cog-Plainte : Evaluation of the cognitive complaint after cancer treatment (radiotherapy +/- chemotherapy)
Clinical
Cog-Reduc : Program of rehabilitation to improve cognitive alterations reported by the patients : randomized and multicentric study.
Clinical/Neuropsychological/Biostatistics
Cog-Sportif: Randomized study on the impact of adapted physical activity sessions on cognitive functions and quality of life in patients with localized breast cancer
Clinical
MoCA: Comparison of MMSE versus MoCA for cognitive evaluation in oncogeriatry
Clinical/Neuropsychological
MoCA2: MoCA versus MMS: which is the best tool for screening of cognitive dysfunction in oncogeriatry?
Clinical/Neuropsychological
TCSEQ: Anatomical, clinical and neuro-psychological evaluation of long-term sequelae in brain cancer patients treated by radiotherapy
Clinical
Cog-Prim: Effects of brain radiotherapy on cognitive performances in the non-human primate (marmoset)
Pre-clinical and biomarkers
ImmunoFog: Evaluation of an anti-cancer immunotherapy targeting the PD-1 / PD-L1 system on cognitive functions, emotional reactivity and neuroinflammation in an animal model
Pre-clinical and biomarkers
Cog-Stim faisabilité: Management of cancer treatments-related cognitive difficulties in women treated for breast cancer : a feasibility study
Clinical
Cog-TabAge: Use of cognitive training software among elderly patients treated for breast cancer: Feasibility Study
Clinical
CHEMO-PARPI-COG: Impact of a combination of chemotherapy and PARPs inhibitors on brain function in a behavioural animal model
Preclinical
CANTO-Cog : Study of chronic toxicity of anticancer treatments in patients with localised breast cancer – cognitive workpackage and ancillary imaging study
Clinical/Neuropsychological/Biostatistics
CANTO-Cog young: Study of the chronic toxicities of anticancer treatments in patients with localized breast cancer under the age of 45 – cognitive aspect and ancillary study imaging.
Clinical/Neuropsychological/Biostatistics
CHEMO-mice : Impact of the chemotherapy 5-fluorouracil on cognitive functions and neuronal plasticity in the mouse
Pre-clinical and biomarkers
BEVA-mice : Evaluation of VEGF immunoneutralisation on mouse cognitive function and brain plasticity
Pre-clinical and biomarkers
mTOR-TT-mice : Evaluation of the impact of everolimus on cognitive function in an animal behavioural model
Pre-clinical and biomarkers
FLUOCAMPTO-mice : Establisment of biorthogonal chemical reactions of cancer drugs to detect chemotherapy in the central nervous system
Pre-clinical and biomarkers
MetaCan : Relationships between cognitive complaints and objective cognitive scores in cancer: metamemory evaluation
Neuropsychological/Biostatistics
Cog-Pro : Impact of hormone-therapy of new generations on elderly patient cognitive functions treated for a metastatic prostate cancer
Clinical/Neuropsychological/Biostatistics
Pre-cog-pro: Impact of new generation hormone-therapy proposed to CRPCa patients on cognitive functions in preclinical models: Evaluation of abiraterone acetate combined with prednisone or Enzalutamide in aged castrated mice
Pre-clinical and biomarkers
Cog-PROSOM-K: Functioning of prospective memory in breast cancer patients: evaluation of the impact of sleep with virtual reality methods
Clinical/Neuropsychological
Cog-PI3K: Effect of PI3K inhibitor cancer targeted therapy on emotional reactivity and cognitive functions in mice
Pre-clinical and biomarkers
exoCancer-Cog: Breast cancer and tumoral exosomes involved in cognitive disorders associated with cancer? Proof of concept study
Pre-clinical and biomarkers
Nutri-Cog: Impact of Qiseng on cognitive functions and fatigue after chemotherapy in mice
Pre-clinical
ICANSLEEP: Impact of sleep disturbances on cognitive deficits in breast cancer patients
Clinical/Neuropsychological
preAP-RT-Brain : Benefit of physical activity in countering the side effects of cerebral radiotherapy: preclinical study in adult rats
Pre-clinical, neuro-imaging and biomarkers
preCog-RT-Brain : Multiparametric and longitudinal evaluation of the effects of brain irradiation in rats: from tissue alterations to cognitive impairments
Pre-clinical, neuro-imaging and biomarkers
Participations
Participations/Collaborations for ancillary cognition studies
OLA-TMZ-RTE-01 : Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients
Clinical
COVIPACT : Impact of the COVID-19 infectious epidemic on the management of patients with cancer and on the psychological consequences for patients and caregivers
Clinical