Comparison of MMSE versus MoCA for cognitive evaluation in oncogeriatry

Coordinator: Marie Lange (Caen)


Clinicians currently use the Mini Mental State Examination (MMSE) to quickly evaluate cognitive functioning as part of the usual geriatric assessment. This aims at identifying patients with possible pathological aging in order to refer them for a deeper cognitive evaluation in neuropsychology. However, studies about various medical contexts have shown that this tool might be less sensitive than the Montreal Cognitive Assessment (MoCA). But those studies only focused on post-treatment cognitive assessment and authors cannot conclude about cognitive impairments before adjuvant-treatment. To our knowledge, no study has specifically compared MoCA versus MMSE among elderly cancer patients.


Compare MMSE versus MoCA among elderly patients who can receive first line cancer treatment and who will undergo an oncogeriatric assessment.

Study methodology

Prospective, multicentric study

Study status

Closed, 66 patients enrolled


CLCC Caen/CHU Caen, with the participation of the « Centre de traitement des données »

Financial support



Rambeau A, Beauplet B, Laviec H, Licaj I, Leconte A, Chatel C, Le Bon P, Denhaerynck J, Clarisse B, Frenkiel N, Lange M, Joly F. Prospective comparison of the Montreal Cognitive Assessment (MoCA) and the Mini Mental State Examination (MMSE) in geriatric oncology. J Geriatr Oncol. 2018 Aug 24. pii: S1879-4068(18)30095-X. doi: 10.1016/j.jgo.2018.08.003. [Epub ahead of print] PubMed PMID: 30150019