Our Works

The organization of our team around the original theme “Cancer and Cognition” led to a a number of scientific advances

COMMUNICATION

Cog-Age : Impact of adjuvant chemotherapy on cognitive functions and quality of life of patients over the age of 65: application to breast cancer

Clinical/Neuropsychological/Biostatistics

  Cog-Age

Cog-Angio : Impact of anti-angiogenic treatments on quality of life and cognitive functions of metastatic renal cell carcinoma adult patients.

Clinical/Neuropsychological/Biostatistics  

Cog-Angio

Cog-Obs : Impact of cognitive functions on observance in patients with oral cancer therapies.

Clinical/Neuropsychological/Biostatistics

Cog-Obs

Cog-Reduc : Program of rehabilitation to improve cognitive alterations reported by the patients : randomized and multicentric study.

Clinical/Neuropsychological/Biostatistics

Cog-Réduc

CanMem : Impact of cancer on functional memory: improving the understanding of impairment using neuropsychological approaches and neuroimaging (complementary project to Cog-Age)

Neuropsychological

CanMem

Cog-Plainte : Evaluation of the cognitive complaint after cancer treatment (radiotherapy +/- chemotherapy)

Clinical  

Cog-Plainte

Cog-Sportif: Randomized study on the impact of adapted physical activity sessions on cognitive functions and quality of life in patients with localized breast cancer

Clinical  

Cog-Sportif

MoCA: Comparison of MMSE versus MoCA for cognitive evaluation in oncogeriatry

Clinical/Neuropsychological

MoCA

MoCA2: MoCA versus MMS: which is the best tool for screening of cognitive dysfunction in oncogeriatry?

Clinical/Neuropsychological

MoCA2

Cog-Prim: Effects of brain radiotherapy on cognitive performances in the non-human primate (marmoset)

Pre-clinical and biomarkers

Cog-PRIM

Cog-PI3K: Effect of PI3K inhibitor cancer targeted therapy on emotional reactivity and cognitive functions in mice

Pre-clinical and biomarkers

Cog-PI3K

Cog-Immuno: Cognitive functions in patients treated by immunotherapy

Clinical

Cog-Immuno

CANTO-Cog : Study of chronic toxicity of anticancer treatments in patients with localised breast cancer – cognitive workpackage and ancillary imaging study

Clinical/Neuropsychological/Biostatistics

CANTO-Cog

CHEMO-mice : Impact of the chemotherapy 5-fluorouracil on cognitive functions and neuronal plasticity in the mouse

Pre-clinical and biomarkers

CHEMO-mice

mTOR-TT-mice : Evaluation of the impact of everolimus on cognitive function in an animal behavioural model

Pre-clinical and biomarkers

mTOR-TT-mice

BEVA-mice : Evaluation of VEGF immunoneutralisation on mouse cognitive function and brain plasticity

Pre-clinical and biomarkers

BEVA-mice

FLUOCAMPTO-mice : Establisment of biorthogonal chemical reactions of cancer drugs to detect chemotherapy in the central nervous system

Pre-clinical and biomarkers

FLUOCAMPTO-mice

MetaCan : Relationships between cognitive complaints and objective cognitive scores in cancer: metamemory evaluation

Neuropsychological/Biostatistics

MetaCan

Cog-Pro : Impact of hormone-therapy of new generations on elderly patient cognitive functions treated for a metastatic prostate cancer

Clinical/Neuropsychological/Biostatistics

Cog-Pro

TCSEQ: Anatomical, clinical and neuro-psychological evaluation of long-term sequelae in brain cancer patients treated by radiotherapy

Clinical

TCSEQ

Cog-PROSOM-K: Functioning of prospective memory in breast cancer patients: evaluation of the impact of sleep with virtual reality methods

Clinical/Neuropsychological

Cog-PROSOM-K

Cancer-Cog: Breast cancer and tumoral exosomes involved in cognitive disorders associated with cancer? Proof of concept study

Pre-clinical and biomarkers

Cancer-Cog

Pre-cog-pro: Impact of new generation hormone-therapy proposed to CRPCa patients on cognitive functions in preclinical models: Evaluation of abiraterone acetate combined with prednisone or Enzalutamide in aged castrated mice

Pre-clinical and biomarkers

Pre-cog-pro

Participations

Participations/Collaborations for ancillary cognition studies

OLA-TMZ-RTE-01 : Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients

Clinique

OLA-TMZ-RTE-01