Randomized study on the impact of adapted physical activity sessions on cognitive functions and quality of life in patients with localized breast cancer

Coordinator: Olivier Rigal (Rouen)


Studies have shown benefits of adapted physical activity (APA) for cancer survivors, especially after breast cancer treatment. APA sessions significantly improve quality of life, emotional well-being, physical abilities and reduce fatigue of patients, without any complication. Benefits of physical activity (light to moderate) on cognitive functions of elderly (especially those with dementia) are also recognized in other pathologies. Therefore, APA could reduce this chemofog and improve the quality of life of patients after their cancer.


Evaluate the benefits of APA sessions on cognitive functions in breast cancer patients treated with chemotherapy.

Study methodology

Randomized, longitudinal, interventional, multicentric study. One group with “immediate APA” versus one group with “postponed APA”. Evaluation after 3 months. Plasmatic biomarkers analyses.

Study status

Open for inclusions, 36/152 patients enrolled.


3 participating centers : CLCC Caen, Lille and Rouen

Financial support

PHRC-I (DGOS) 2015