List of main publications


Long-term fatigue and cognitive disorders in breast cancer survivors. Florence Joly, Marie Lange, Mélanie Dos Santos, Ines Vaz-Luiz, Antonio Di-Meglio. Cancers, Special Issue “Treatment Strategies and Survival Outcomes in Breast Cancer” (accepted)


Cancer-Related Cognitive Impairment: An update on state of the art, detection, and management strategies in cancer survivors. Lange M, Joly F, Vardy J, Ahles T, Dubois M, Tron L, Winocur G, De Ruiter MB, Castel H. Ann Oncol. 2019 Oct 16.pii: mdz410. doi: 10.1093/annonc/mdz410. [Epub ahead of print] PubMed PMID:31617564.


How to assess and manage cognitive impairment induced by treatments of non-central nervous system cancer. Lange M, Castel H, Le Fel J, Tron L, Maillet D, Bernaudin M, Touzani O, Perrier J, Boone M, Licaj I, Giffard B, Dubois M, Rigal O, Durand T, Belin C, Ricard D, Le Gal R, Pancré V, Hardy-Léger I, Joly F. Neurosci Biobehav Rev. 2019 Sep 22. pii: S0149-7634(19)30478-6. doi:10.1016/j.neubiorev.2019.09.028. [Epub ahead of print] Review. PubMed PMID:31553925.


Potential impact of immunotherapy agents on cognitive function in cancer patients. Joly F, Castel H, Tron L, Lange M, Vardy J. J Natl Cancer Inst. 2019 Aug 26. pii: djz168. doi: 10.1093/jnci/djz168. [Epub ahead of print] PubMed PMID:31504664.


Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol  (2019). Paul Lesueur, Justine Lequesne, Jean-Michel Grellard, Audrey Dugué, Elodie Coquan, Pierre-Emmanuel Brachet Julien Geffrelot, Evelyne Emery, Hassanein Berro, Laurent Castera, Nicolas Goardon, Joëlle Lacroix, Marie Lange, Aurélie Capel, Alexandra Leconte, Benoit Andre, Angélique Léger, Anais Lelaidier , Bénédicte Clarisse, Dinu Stefan. BMC Cancer, 19(1):198. doi: 10.1186/s12885-019-5413-y.


Cognitive complaints in cancer survivors and expectations for support: Results from a web-based survey. Lange M, Licaj I, Clarisse B, Humbert X, Grellard JM, Tron L, Joly F. Cancer Med. 2019 Mar 18. doi: 10.1002/cam4.2069. [Epub ahead of print] PubMed PMID: 30884207.


Impact of anxio-depressive symptoms and cognitive function on oral anticancer therapies adherence. Dos Santos M, Lange M, Gervais R, Clarisse B, Capel A, Barillet M, Grellard JM, Heutte N, Licaj I, Joly F. Support Care Cancer. 2019 Jan 28. doi: 10.1007/s00520-019-4644-4. [Epub ahead of print] PubMed PMID: 30690685.



Longitudinal investigation of cognitive deficits in breast cancer patients and their gray matter correlates: impact of education level. Perrier J, Viard A, Levy C, Morel N, Allouache D, Noal S, Joly F, Eustache F, Giffard B. Brain Imaging Behav. 2018 Nov 7. doi: 10.1007/s11682-018-9991-0. [Epub ahead of print] PubMed PMID: 30406352.


Impact of breast cancer on prospective memory functioning assessed by virtual reality and influence of sleep quality and hormonal therapy: PROSOM-K study. Duivon M, Perrier J, Joly F, Licaj I, Grellard JM, Clarisse B, Lévy C, Fleury P, Madeleine S, Lefèvre N, Rauchs G, Lecouvey G, Fraisse F, Viader F, Eustache F, Desgranges B, Giffard B. BMC Cancer. 2018 Sep 3;18(1):866. doi:10.1186/s12885-018-4762-2. PubMed PMID: 30176833; PubMed Central PMCID:PMC6122719.


[Actualités sur la plainte cognitive associée au cancer du sein : la mémoire prospective, une mémoire oubliée.] Duivon M, Perrier J, Desgranges B, Giffard B (2018). Rev Neuropsychol, 10 (3) : 222-31.


Prospective comparison of the Montreal Cognitive Assessment (MoCA) and the Mini Mental State Examination (MMSE) in geriatric oncology. Rambeau A, Beauplet B, Laviec H, Licaj I, Leconte A, Chatel C, Le Bon P, Denhaerynck J, Clarisse B, Frenkiel N, Lange M, Joly F. J Geriatr Oncol. 2018 Aug 24. pii: S1879-4068(18)30095-X. doi: 10.1016/j.jgo.2018.08.003. [Epub ahead of print] PubMed PMID: 30150019


 Cognitive Changes After Adjuvant Treatment in Older Adults with Early-Stage Breast Cancer. Lange M, Heutte N, Noal S, Rigal O, Kurtz JE, Lévy C, Allouache D, Rieux C, Lefel J, Clarisse B, Leconte A, Veyret C, Barthélémy P, Longato N, Tron L, Castel H, Eustache F, Giffard B, Joly F. The Oncologist. 2018 Jun 22. pii: theoncologist.2017-0570. doi: 10.1634/theoncologist.2017-0570. [Epub ahead of print] PubMed PMID: 29934409.


 Chemotherapy and cognition: International cognition and cancer task force recommendations for harmonising preclinical research. Winocur G, Johnston I, Castel H. Cancer Treat Rev. 2018 Jun 1;69:72-83. doi: 10.1016/j.ctrv.2018.05.017. [Epub ahead of print] Review. PubMed PMID: 29909223.


Sexual Disorders of Patients With Metastatic Renal Cell Carcinoma (mRCC) Treated With Antiangiogenic Therapies. Denouel A, Heutte N, Escudier B, Kurtz JE, Santos MD, Longato N, Desrues L, Dauchy S, Lange M, Sevin E, Rieux C, Clarisse B, Castel H, Noal S, Joly F. Clin Genitourin Cancer.2018 May 21. pii:
S1558-7673(18)30286-6. doi: 10.1016/j.clgc.2018.05.013. [Epub ahead of print] PubMed PMID: 30007862.


How to Identify and Manage Cognitive Dysfunction After Breast Cancer Treatment. Lange M, Joly F. J Oncol Pract. 2017 Dec;13(12):784-790. doi:10.1200/JOP.2017.026286. PubMed PMID: 29232539.


Impact of new generation hormone-therapy on cognitive function in elderly patients treated for a metastatic prostate cancer: Cog-Pro trial protocol. Lange M, Laviec H, Castel H, Heutte N, Leconte A, Leger I, et al. BMC Cancer. 2017;17(1):549.


Biomarkers Associated with Cognitive Impairment in Treated Cancer Patients: Potential Predisposition and Risk Factors. Castel, H., Denouel, A., Lange, M., Tonon, M-C., Dubois, M., Joly, F. (2017).Frontiers in Pharmacology, 8: 138


[Cognitive complaints induced by cancer treatments in oncology]. Lange, M., Léger, I. La lettre du Cancérologue Vol. XXVI – n° 4 – avril 2017


Cognitive complaints in breast cancer patients treated with chemotherapy: a reality? Lange M, Joly F. Transl Cancer Res 2017;6(Suppl 3):S461-S463. doi: 10.21037



Decline in cognitive function in older adults with early-stage  breast cancer after adjuvant treatment. Lange M., Heutte N., Rigal O., Noal S, Kurtz J-E., Lévy C., Allouache D., Rieux C., Lefel J., Clarisse B., Veyret C., Barthélémy P., Longato N., Eustache F., Giffard B., Joly F. The Oncologist. 2016;  21(11), 1337-1348.


Prospective evaluation of the impact of antiangiogenic treatment on cognitive functions in metastatic renal cancer. Joly F., Heutte N., Duclos B., Noal S., Léger I., Dauchy S., Longato N., Desrues L., Houédé N., Lange M., Sevin E., Rieux C., Clarisse B., Castel H., Escudier B. European Urology Focus. 2016, 2(6), 642-649



Impact of cancer and treatments on cognitive functions: Advances in research from the Paris International Cognition and Cancer Task Force Symposium and update since then. Joly F., Giffard B., Rigal O., De Ruiter M.B., Small B.J. Dubois M., LeFel J.,  Schagen S.B., Ahles T.A. Wefel J.S., Vardy J.L. Pancré V., Lange M., Castel H. J Pain Symptom Manage. 2015; 50(6), 830-841.


Emotional specificities of autobiographical memory after breast cancer diagnosis. Morel N., Dayan J., Piolino P., Viard A., Allouache D., Noal S., Levy C., Joly F., Eustache F., Giffard B. Consciousness and Cognition 2015 Sept; 35, 42-52.


Cognitive complaints in cancer: The French version of the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog), normative data from a healthy population. Lange M., Heutte N., Morel N., Eustache F., Joly F., Giffard B. Neuropsychol Rehabil. 2015 May 7:1-18.


[Mild cognitive deficits in cancer: their clinical assessment and management]. Giffard, B., Lange, M., Léger, L. Revue de neuropsychologie. 2015, 7(2), 127-134.


Monitoring and optimising cognitive functioning cancer patients: Present knowledge and future directions. Schagen S.B., Klein M., Reijneveld J.C., Brain E., Deprez S., Joly F., Scherwath A., Schrauwen W., Wefel J.S.. EJC Supplements 2014: 29–40.


Cognitive dysfunctions in elderly cancer patients: a new challenge for oncologists. Lange M., Rigal O., Clarisse B., Giffard B., Sevin E., Barillet M., Eustache F., Joly F. Cancer Treatment Rev 2014 Jul; 40(6):810-7.


Baseline cognitive functions among elderly patients with localized breast cancer. Lange M., Giffard B., Noal S., Rigal O., Kurtz J-E., Heutte N., Lévy C., Allouache D., Rieux C., Lefel J., Daireaux A., Clarisse B., Veyret C., Barthélémy P., Longato N., Eustache F., Joly F. Eur J Cancer. 2014 Sep; 50(13):2181-9.


Chemotherapy-induced long-term alteration of executive functions and hippocampal cell proliferation: role of glucose as adjuvant. Dubois M., Lapinte N., Villier V., Lecointre C., Roy V., Tonon MC., Gandolfo P., Joly F., Hilber P., Castel H. Neuropharmacology. 2014; 79:234-48.


Evaluation of the impact of the cancer therapy everolimus on the central nervous system in mice. Dubois M., Le Joncour V., Tonon MC., Anouar Y., Proust F., Morin F., Gandolfo P., Joly F., Hilber P., Castel H. PLoS One. 2014;1;9-12.



[Impact of cancer treatments on cognitive functions: the patients’ view, their expectation and their interest in participating to cognitive rehabilitation workshops]. Le Fel J., Daireaux A., Vandenbosshe S., Heutte N., Rigal O., Rovira K., Joly F,. Roy V. Bull Cancer. 2013 ;100 (3):223-9.


Autobiographical memory, self, and stress-related psychiatric disorders: which implications in cancer patients? Giffard B., Viard A., Dayan J., Morel N., Joly F., Eustache F. Neuropsychol Rev. 2013;23 157-68.


Impact of antiangiogenic treatment on cognitive functions and fatigue in metastatic renal cancer patients. Joly F., Noal S., Heutte N., Leger I., Duclos B., Lange M., Longato N., Dauchy S., Clarisse B., Escudier B. ESMO congress, Amsterdam sept 2013.


[A memory consultation in oncology: between complaint and disorder…]. Léger I., de Batz L., Dauchy S. Psycho-Oncologie. 2013, 7, 210-216.


Synthesis, Biological Evaluation, and in Vivo Imaging of the first Camptothecin-Fluorescein Conjugate. Chevalier A., Dubois M., Le Joncour V., Dautrey S., Lecointre C., Romieu A., Renard PY., Castel H., Sabot C. Bioconjug Chem. 2013 Jun 24.



French version of the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) version 3. Joly F., Lange M., Rigal O., Correia H., Giffard B., Beaumont JL., Clisant S., Wagner L. Support Care Cancer. 2012; 20:3297-305.



Cognitive dysfunction and cancer: which consequences in terms of disease management? Joly F., Rigal O., Noal S., Giffard B. Psychooncology. 2011 Dec;20(12):1251-8.


One-year longitudinal study of fatigue, cognitive functions, and quality of life after adjuvant radiotherapy for breast cancer. Noal S., Levy C., Hardouin A., Rieux C., Heutte N., Ségura C., Collet F., Allouache D., Switsers O., Delcambre C., Delozier T., Henry-Amar M., Joly F. Int J Radiat Oncol Biol Phys. 2011 Nov 1; 81(3):795-803.


[Impact of adjuvant chemotherapy on cognitive functions in breast cancer: literature review]. Lange M., Giffard B., Eustache F., Morel N., Noal S. & Joly F. Psycho-oncologie, 2011; 5(1), 3-10.



[The impact of cancer and its treatment on cognitive function: the example of breast cancer]. Morel N., Eustache F., Lange M., Joly F., Giffard B. Revue de neuropsychologie 2010: 2(3), 250 – 254.



[Cognitive functions and cancer]. Joly.F. Bull Cancer 2008 ; 95 (11) : 1131-2