OLA-TMZ-RTE-01

Participation within the framework of the platform (ancillary part of a clinical study)

Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients

Coordination: Stefan D. (Caen)

Status : Open, 30 patients enrolled/79

Sponsors: PHRC-K, INCa-DGOS

Promotion: CLCC Caen

Publications :

• Paul Lesueur, Justine Lequesne, Jean-Michel Grellard, Audrey Dugué, Elodie Coquan, Pierre-Emmanuel Brachet Julien Geffrelot, Evelyne Emery, Hassanein Berro, Laurent Castera, Nicolas Goardon, Joëlle Lacroix, Marie Lange, Aurélie Capel, Alexandra Leconte, Benoit Andre, Angélique Léger, Anais Lelaidier , Bénédicte Clarisse, Dinu Stefan. Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol  (2019). BMC Cancer, 19(1):198. doi: 10.1186/s12885-019-5413-y.